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USMLE STEP 1 Recommendations
USMLE Step 1 Study Principles
Phases of STEP Preparation
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Didactic Phase – Longest phase, focused on foundational knowledge and includes M1 and M2 curriculum.
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Content Phase – Intensive and focused content review, typically the first 2-4 weeks of dedicated study.
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Test Prep Phase (Last 1-2 weeks before the exam) – Focus on testing skills, test-taking strategy, simulated question blocks in a test-like environment, self-assessments, and final content reinforcement.
Understanding the Exam
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USMLE Step 1 = A Basic Science Exam
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Prioritizes application of physiology, anatomy, and microbiology.
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Emphasizes mechanisms over rote memorization.
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Core Resources for Content Review (Resources and Links Listed Below)
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UWorld – The cornerstone of Step 1 prep
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Approach questions systematically.
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Identify key phrases and concepts.
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Differentiate critical information from distractors.
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Analyze all answer choices (why they’re right or wrong).
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Hypothesize how changes in the vignette could alter correct answers.
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Maximizing UWorld Effectiveness
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Active Learning: UWorld Notebook
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Write down one or more key takeaways per question (new fact, forgotten detail, high-yield point).
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Option: Convert notes into Anki flashcards for spaced repetition.
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UWorld is for learning, NOT assessment – Read explanations in detail, even for correct answers.
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Question Block Strategies
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Random Question, Timed Blocks = Best for self-assessment and tracking progress.
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Subject-Specific, Tutor Mode Blocks = Useful for targeted content mastery.
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Quality > Quantity – Thoughtful review of a few questions beats rushing through many.
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Dedicated Study Recommendation - A Two Phase Approach
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Content Phase
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Master your medical school curriculum – it's designed for long-term retention.
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Integrate physiology, anatomy, and microbiology with every system.
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Few, high-yield UWorld questions > Volume-based approach.
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Example study day with a system-based approach
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1. Targeted Review of Prior Days Material (ex. Anki Card/Uworld Notes) ​
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2. Pre-Test on the Days System (20-40 question Uworld, untimed, tutor mode, system specific)
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3. Content Review (Majority of day) - Primary materials focused on the targeted body system with focuses on the integration of physiology and basic sciences in the setting of pathologic disease (First Aid, Pathoma, etc.)
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4. Post-Test on System (40 question Uworld, untimed, tutor mode, system specific)
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5. Make notes/Write Anki cards to review the following morning on missed questions
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6. Optional: Brief Test Prep - 20 question block, timed, random systems
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Testing Phase​
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Strong test-taking skills help, but content mastery is essential. It is impossible to completely mask content deficiencies with strong test-taking skills. Therefore it is vital you have mastered the content phase before moving to this phase.
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The focus of the phase is the application of learned content in a simulated testing environment
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The goal - see as many questions and vignettes as possible while applying your knowledge
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Example study day
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1. Targeted review of prior material ​
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2. Test Block (40 Questions, random, timed)
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3. Review missed questions
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4. Return to primary resources as needed to fill content gaps
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5. Repeat steps 2-4 as many times as possible
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Recommended Resources
Uworld
Resource Description
UWorld is a comprehensive question bank designed to simulate the USMLE Step 1 exam. It features high-yield clinical vignettes, detailed explanations, and high-quality images to reinforce key concepts. Each question includes thorough answer explanations, covering not just the correct choice but also why other answers are incorrect, making it an essential tool for self-assessment and knowledge reinforcement.
Why Recommended
Uworld is the single most high-yield resource for Step 1 preparation. Mimicking the structure of USMLE exam questions, the detailed explanations provide insight into both correct and incorrect answers, making it an essential learning tool.​
First Aid for the USMLE Step 1
Resource Description
First Aid for the USMLE Step 1 is the gold-standard review book for Step 1 preparation. It provides a concise yet comprehensive overview of key concepts, organized by subject and system, with mnemonics, illustrations, and high-yield facts. Updated annually, it integrates student feedback to ensure relevance and accuracy.
Why Recommended
​First Aid serves as a foundation for Step 1 review, consolidating information into a structured and easy to navigate format. The integration of mnemonics, clinical correlations, and frequently tested concepts aid in content review. Usuful for pointing you in the direction for more in-depth study.
Dirty Medicine (YouTube)
Resource Description
Dirty Medicine is a YouTube channel that provides high-yield, straightforward explanations of complex medical topics. The videos focus on breaking down difficult concepts into simple, easy-to-understand segments, often incorporating humor and visual aids to enhance retention.
Why Recommended
​Dirty Medicine provides clear, no-nonsense explanations of challenging topics, often breaking down complex ideas into simple, memorable components. The informal teaching style and strong conceptual focus make it a valuable supplement for reinforcing difficult subjects. Specifically recommended as an excellent biochemistry review
Sketchy Pharm/Micro
Resource Description
Sketchy is a visual learning resource that uses storytelling and mnemonics to help students retain relevant medical concepts. Each drug and bug is presented through creative, story-based illustrations that link mechanisms, side effects, and clinical uses to memorable imagery.
Why Recommended
​Sketchy transforms learning into an engaging, memorable experience. It enhances long-term retention and is a familiar site for learners and can hit common tested topics quickly.
Scholar Rx Bricks
Resource Description
Scholar Rx Bricks is a modular learning platform that provides interactive, case-based lessons for medical students. Each "brick" is a self-contained module covering key concepts in an engaging, structured format, integrating text, images, and quiz questions to reinforce learning.
Why Recommended
​Scholar Rx Bricks provides interactive, case-based learning modules that break down complex topics into digestible components. The platform is excellent for reinforcing foundational knowledge in a structured, stepwise manner, making it a great supplement to traditional resources. Best used for more in-depth reading on challenging topics.
CBSSA Exams
Resource Description
The CBSSA exams, created by NBME, are official self-assessments designed to mimic the structure and difficulty of the USMLE Step 1. These practice tests provide scaled scores predictive of real exam performance and detailed feedback on strengths and weaknesses to guide further study.
Why Recommended
​NBME CBSSA exams are the most reliable predictors of Step 1 performance. They mostly mirror the format and style of actual USMLE questions, allowing students to gauge their readiness, identify weak areas, and fine-tune their test-taking strategies in the final weeks before the exam. Recommend taking a self-assessment every 1-2 weeks during dedicated study.