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General Study Strategy
Internal Medicine

Rotation Specific Overview

Internal medicine emphasizes comprehensive patient care, diagnostic reasoning, and managing complex chronic conditions. It often involves extensive rounding, detailed patient histories, physical examinations, and meticulous documentation. Success hinges on developing robust clinical reasoning skills, synthesizing vast amounts of medical knowledge, and effectively managing your study time to cover a wide array of pathologies. Prioritize high-yield clinical conditions, diagnostic algorithms, evidence-based treatments, and interpreting diagnostic studies.

 

Core Principles and Focus Areas

  • Diagnostic Reasoning and Clinical Problem-Solving:

    • Develop systematic approaches to common presentations such as chest pain, dyspnea, abdominal pain, altered mental status, and fever of unknown origin.

    • Emphasize differential diagnosis formation and stepwise diagnostic evaluation.

  • Chronic Disease Management:

    • Understand evidence-based management for chronic diseases including diabetes mellitus, hypertension, heart failure, chronic kidney disease, COPD/asthma, and coronary artery disease.

    • Focus on guideline-directed therapies and recognize common complications.

  • Acute Hospital Management:

    • Master initial evaluation and stabilization of acute conditions such as acute coronary syndrome, pulmonary embolism, sepsis, stroke, acute kidney injury, GI bleeding, and electrolyte disturbances.

    • Understand inpatient management protocols and criteria for ICU/step-down care.

  • Preventive and Evidence-Based Medicine:

    • Integrate preventive screening guidelines (USPSTF), cancer screening, immunization recommendations, and evidence-based medicine principles into clinical practice.

    • Emphasize appropriate utilization of resources, tests, and clinical decision rules.

  • Interpretation of Laboratory and Imaging Results:

    • Develop skills to interpret routine labs (CBC, CMP, ABGs, urinalysis), cardiac biomarkers, coagulation studies, and imaging (X-ray, CT, MRI, ultrasound) within clinical contexts.

  • Pharmacology and Therapeutics:

    • Familiarize yourself with common medication classes used in internal medicine (antibiotics, antihypertensives, anticoagulants, diabetic medications) including mechanisms, indications, adverse effects, and monitoring parameters.

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Core Resources (Resources, Links, and More Detailed Descriptions Listed Below) 

  • UWorld/Amboss Qbanks – The cornerstones of practicing rotation-specific knowledge 

    • Approach questions systematically, identify key phrases and concepts, differentiate critical information from distractors, analyze all answer choices (why they’re right or wrong), and hypothesize how changes in the vignette could alter correct answers.

  • Case Files: Internal Medicine

    • ​Excellent for practice questions, scenario-based learning, and real-world case discussions

  • BRS IM/Blueprints/First Aid (Prep-book resources) 

    • Important resources for structured review to pair with practice questions and for diving deeper into material. ​

  • NBME Practice Exams 

    • Pivotal for evaluating progress throughout the rotation. Target your first NBME for the mid-point of the rotation followed by a NBME every 1-1.5 weeks following​

 

Maximizing UWorld Effectiveness

  • Active Learning: UWorld Notebook

    • Write down one or more key takeaways per question (new fact, forgotten detail, high-yield point).

      • Option: Convert notes into Anki flashcards for spaced repetition.

    • UWorld is for learning, NOT assessment – Read explanations in detail, even for correct answers.

  • Question Block Strategies

    • Random Question, Timed Blocks = Best for self-assessment and tracking progress.

    • Subject-Specific, Tutor Mode Blocks = Useful for targeted content mastery. This should be the focus for the majority of your rotation

    • Quality > Quantity – A thoughtful review of a few questions beats rushing through many.

 

General Approach to Studying on the Wards

  • Weekly Topics: Dedicate each week to core internal medicine topics. Align these with your clinical rotations.

  • Daily Integration/Practice: Allocate daily review sessions to UWorld practice questions and corresponding Anki reviews for spaced repetition. Recommended to break down the total number of Uworld questions for the rotation and schedule a set number a day that will put you on pace to finish by 1 week before the shelf exam. 

  • Longitudinal Learning: Regularly revisit health maintenance guidelines (USPSTF) and common clinical presentations throughout the rotation as patients present to the clinic/on the wards. 

  • Pre-Clinic/Ward Preparation: Briefly review anticipated patient presentations or conditions prior to clinical encounters to enhance engagement and confidence.

  • Post-Clinic Reflection: After clinical experiences, revisit related guidelines or resources (e.g., CDC vaccine schedule, pediatric treatment guidelines) to deepen understanding of real-life application.

Recommended Question Banks

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Uworld 

Resource Description 

UWorld is a comprehensive question bank designed to simulate the USMLE STEP exams. It features high-yield clinical vignettes, detailed explanations, and high-quality images to reinforce key concepts. Each question includes thorough answer explanations, covering not just the correct choice but also why other answers are incorrect, making it an essential tool for self-assessment and knowledge reinforcement.

Why Recommended

Uworld is the single most high-yield resource for testing preparation. Mimicking the structure of exam questions, the detailed explanations provide insight into both correct and incorrect answers, making it an essential learning tool.​  Recommended to complete all rotation-specific questions prior to the shelf. 

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Resource Description 

Amboss question bank offers an alternative to Uworld as a tool to practice answering multiple choice questions in a clinical vignette style. Each question includes a detailed explanation and links to relevant material for further education. 

Why Recommended

Great alternative/pair with Uworld. Focus differs slightly from Uworld while hitting the most salient points required for the NBME exam. Has a phone app version that can allow questions to be answered on the move or in downtime during rounds. 

Textbook Resources

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Step Up to Internal Medicine

Resource Description 

Step-Up series is a high-yield, outline-style review book that emphasizes testable content with margin “Quick Hits” and clinical reasoning algorithms. It covers core conditions with concise details on presentation, workup, and management.

Why Recommended

Students appreciate this resource for its focused content and practical algorithms, making it ideal for quickly preparing for the Pediatric Shelf and Step 2 CK questions.

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Case Files Internal Medicine

Resource Description 

Case Files uses realistic patient cases to teach diagnostic reasoning and clinical management through USMLE-style questions, high-yield discussions, and practical clinical pearls. The updated format improves readability with bulleted summaries and clear organization.

Why Recommended

Students value this resource for building clinical reasoning skills and preparing for exams through real-world scenarios that mirror the style and depth of shelf and Step 2 CK questions.

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Blueprints Medicine

Resource Description 

Blueprints offers a concise yet comprehensive review tailored for a 4–6 week medicine clerkship. It features updated management strategies, case vignettes, drug highlights, review questions, and chapter summaries.

Why Recommended

Students find it useful for both clinical shifts and exam prep due to its clear structure, high-yield summaries, and practical content that bridges textbook learning with real patient care.

Recommended Videos

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Dr. High Yield

Resource Description 

Dr. High Yield series is a streamlined video and notes resource focused on the most testable, high-yield topics for rotations and Step 2 CK, delivered in a fast-paced, board-style review format. Has study notes for purchase on amazon here.

Why Recommended

Students appreciate its efficiency and direct focus on what’s most likely to be tested, making it ideal for last-minute review or reinforcing core concepts in a time-crunched schedule.

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Emma Holliday

Resource Description 

Emma Holliday's High-Yield Lectures are a series of concise, two-hour video presentations covering key topics in Internal Medicine, Surgery, Pediatrics, and Psychiatry. Each lecture is accompanied by downloadable slides, facilitating an interactive and comprehensive review experience

Why Recommended

Students find these lectures valuable for their focused, high-yield content that aligns well with clinical rotations and exam preparations. The combination of video lectures and accompanying slides enhances understanding and retention of essential concepts.

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Divine Intervention

Resource Description 

Divine Intervention is a widely used podcast and study resource offering high-yield audio reviews, rapid review notes, and clinical vignettes across all core clerkships and Step exams. Topics are explained clearly with a focus on test-taking strategies and clinical reasoning.

Why Recommended

Students recommend Divine Intervention for its thorough yet accessible explanations, especially when commuting or reviewing on the go. It’s particularly praised for clarifying tough concepts and boosting shelf and Step 2 CK performance.

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